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Recombinant Human Leukemia inhibitory factor protein (LIF) (Active)

Recombinant Human Leukemia inhibitory factor protein (LIF) (Active)

Item no.	BM-RPC26663-100ug
Manufacturer	Biomatik
Amount	100ug
Category	Oncology Metabolism Diabetes Glucose Homeostasis Peptides & Proteins Recombinant Proteins Obesity By Organ Skin Cancer Heart & Blood Cancer
Type	Proteins Recombinant
Specific against	Human (Homo sapiens)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	LIF, D factor, Melanoma-derived LPL inhibitor, MLPLI, Emfilermin
Similar products	LIF, D factor, MLPLI, Melanoma-derived LPL inhibitor, Emfilermin
Available
Gene Name	LIF, HILDA
Alternative Names	LIF, D factor, Melanoma-derived LPL inhibitor, MLPLI, Emfilermin
Uniprot	P15018
Source	E.coli
Expression Region	23-202aa
AA Sequence	SPLPITPVNA TCAIRHPCHN NLMNQIRSQL AQ LNGSANAL FILYYTAQGE PFPNNLDKLC GPNV TDFPPF HANGTEKAKL VELYRIVVYL GTSLGN ITRD QKILNPSALS LHSKLNATAD ILRGLLSN VL CRLCSKYHVG HVDVTYGPDT SGKDVFQKKK LGCQLLGKYK QIIAVLAQAF
Sequence Info	Full Length of Mature Protein
Tag Info	Tag-Free
Theoretical MW	19.7 kDa
Purity	>98% as determined by SDS-PAGE and HPLC.
Storage Buffer	Lyophilized from a 0.2 um filtered PBS, pH 7.4
Endotoxin Level	Less than 1.0 EU/ug as determined by LAL method.
Biological Activity	The ED50 as determined by the dose-dependent proliferation of human TF-1 cells is less than 0.1 ng/ml, corresponding to a specific activity of ? 1.0 x 107 IU/mg.
Shipping Condition	Ice packs
Storage	Short term: -20CC; Long term: -80CC. Minimize freeze and thaw cycles.
Expiry Date	1 year
Restriction	For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance	LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.
Function	LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.
Subcellular location	Secreted
Protein Families	LIF/OSM family
Paythway	Jak-STATsignalingpathway

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

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Delivery expected until 9/4/2025

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