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Mercaptopurine (6-MP)

Mercaptopurine (6-MP)

Item no.	V1452-2g
Manufacturer	InvivoChem LLC
CASRN	50-44-2
Amount	2 g
Quantity options	10 g 1 g 250 mg 500 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V1452CAS #:50-44-2Purity >=98% Description: Mercaptopurine (also called 6-MP; 6-Thiohypoxanthine; 6-thiopurine; 6-mercaptopurine; Purinethol) is an approved anticancer medication used to treat malignancies. It is also an immunosuppressive agent widely used for treating autoimmune diseases such as rheumatic diseases, dermatologic conditions, inflammatory bowel disease, and solid organ transplant rejection. It acts by inhibiting the de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA. Description: References: Eur J Clin Pharmacol. 2008 Aug; 64(8):753-67; Am J Hum Genet. 1980 Sep; 32(5):651-62. References: Related CAS #: 6112-76-1 (hydrate); 50-44-2 (free) Related CAS #: 6112-76-1 (hydrate); 50-44-2 (free)
Molecular Weight (MW)	152.18
Formula	C5H4N4S
CAS No.	50-44-2
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 30 mg/mL (197.1 mM)
	Water: < 1 mg/mL
	Ethanol:< 1 mg/mL
Other info	Chemical Name: 1H-purine-6(7H)-thione. InChi Key: GLVAUDGFNGKCSF-UHFFFAOYSA-N InChi Code: InChI=1S/C5H4N4S/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H, (H2, 6, 7, 8, 9, 10) SMILES Code: S=C1NC=NC2=C1NC=N2
Synonyms	6-MP; 6-Thiohypoxanthine; 6-thiopurine; 6-mercaptopurine

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