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Description: Rufinamide (also known as CGP 33101; E 2080; RUF 331) is a voltage-gated sodium channel blocker and a novel antiepilepic agent. It is a board spectrum anticonvulsant that is used in combination with other medication and therapy to treat Lennox–Gastaut syndrome and various other seizure disorders. Rufinamide has efficacy for partial seizures. Rufinamide prolongs the inactivation of sodium channels and limits the frequency of action potential firing in cultured and acutely isolated neurons.
References: Int J Clin Pract. 2006 Nov; 60(11):1497-501; J Vet Pharmacol Ther. 2012 Dec; 35(6):529-33
Chemical Name: 1-(2, 6-difluorobenzyl)-1H-1, 2, 3-triazole-4-carboxamide
InChi Key: POGQSBRIGCQNEG-UHFFFAOYSA-N
InChi Code: InChI=1S/C10H8F2N4O/c11-7-2-1-3-8(12)6(7)4-16-5-9(10(13)17)14-15-16/h1-3, 5H, 4H2, (H2, 13, 17)
SMILES Code: O=C(C1=CN(CC2=C(F)C=CC=C2F)N=N1)N
E-2080; RUF-331; E2080; RUF331; E 2080; RUF 331; CGP-33101; CGP 33101; CGP33101; Trade names: BANZEL; Inovelon.
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.
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Delivery expected until 9/4/2025
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