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Description: HDAC-IN-4 (also known as CXD101, AZD9468) is a novel and potent inhibitor of histone deacetylase (HDAC) with potential anticancer activity, it is extracted from patent WO/2007045844 A1 20070426. Histone deacetylases (HDACs), a family of enzymes involved in epigenetic regulation, have been implicated in the control of synaptic plasticity, as well as learning and memory. HDAC-IN-4 has structural similarities to mocetinostat, MS-275, and JNJ-26481585.
References: Bioorg Med Chem. 2018 Feb 1; 26(3):747-757; WO/2007045844 A1 20070426.
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