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Asunaprevir

Asunaprevir

Item no.	V3153-25mg
Manufacturer	InvivoChem LLC
CASRN	630420-16-5
Amount	25 mg
Quantity options	100 mg 10 mg 250 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V3153CAS #:630420-16-5Purity >=98% Description: Asunaprevir (formerly known as BMS-650032, brand name in Japan and Russia: Sunvepra) is a potent and orally bioavailable small molecule inhibitor of the hepatitis C virus (HCV) enzyme serine protease NS3 with an IC50 of 0.2 nM-3.5 nM. Hepatitis C virus (HCV) enzyme serine protease NS3 is necessary for protein processing during viral replication. Asunaprevir is an experimental drug candidate for the treatment of hepatitis C. It is being tested in combination with pegylated interferon and ribavirin, as well as in interferon-free regimens with other direct-acting antiviral agents including daclatasvir. It is currently in Phase III clinical trials. Description: References: Front Microbiol. 2017; 8: 668; Antimicrob Agents Chemother. 2012 Oct; 56(10):5387-96. References:
Molecular Weight (MW)	748.29
Formula	C35H46ClN5O9S
CAS No.	630420-16-5
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: > 100 mg/mL (133.6 mM)
	Water: < 1 mg/mL
	Ethanol: > 100 mg/mL (133.6 mM)
SMILES	1, 1-dimethylethyl ((1S)-1-{((2S, 4R)-4-(7-chloro-4-methoxyisoquinolin-1-yloxy)-2-({(1R, 2S)-1-((cyclopropylsulfonyl)carbamoyl)-2-ethenylcyclopropyl}carbamoyl) pyrrolidin-1-yl)carbonyl}-2, 2-dimethylpropyl)carbamate
Synonyms	BMS-650032; BMS 650032; BMS650032
SMILES Code	O=C(OC(C)(C)C)N[CH](C(N1[CH](C(N[C]2(C(NS(=O)(C3CC3)=O)=O)[CH](C=C)C2)=O)C [CH](OC4=NC=C(OC)C5=C4C=C(Cl)C=C5)C1)=O)C(C)(C)C

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Amount: 25 mg

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Delivery expected until 11/6/2025

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