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abt-288

abt-288

Item no.	V4312-50mg
Manufacturer	InvivoChem LLC
CASRN	948845-91-8
Amount	50 mg
Quantity options	100 mg 10 mg 250 mg 25 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4312CAS #:948845-91-8Purity >=98% Description: ABT-288 is a novel, potent and highly selective histamine-3 receptor antagonist which demonstrated efficacy across several preclinical cognitive domains, and safety in healthy subjects and elderly volunteers. However, it did not demonstrate efficacy in the symptomatic treatment of Alzheimer's dementia in a randomized, double-blind, placebo- and active-controlled, parallel group design with pre-defined futility criteria to permit early study termination. References: J Alzheimers Dis. 2014; 42(3):959-71.
	Name: ABT-288 CAS#: 948845-91-8 Chemical Formula: C23H24N4O Exact Mass: 372.195 Molecular Weight: 372.472 Elemental Analysis: C, 74.17; H, 6.49; N, 15.04; O, 4.30
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: ABT-288; ABT288; ABT 288 IUPAC/Chemical Name: 2-[4-[4-[(3aR, 6aR)-5-methyl-2, 3, 3a, 4, 6, 6a-hexahydropyrrolo[3, 2-c]pyrrol-1-yl]phenyl]phenyl]pyridazin-3-one InChi Key: GNIRITULTPTAQW-KNQAVFIVSA-N InChi Code: InChI=1S/C23H24N4O/c1-25-15-19-12-14-26(22(19)16-25)20-8-4-17(5-9-20)18-6-10-21(11-7-18)27-23(28)3-2-13-24-27/h2-11, 13, 19, 22H, 12, 14-16H2, 1H3/t19-, 22+/m1/s1 SMILES Code: O=C1C=CC=NN1C2=CC=C(C3=CC=C(N4CC[C]5([H])CN(C)C[C]54[H])C=C3)C=C2

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Amount: 50 mg

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Delivery expected until 11/6/2025

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