Comparison

NSC-95397

Item no. V4941-100mg
Manufacturer InvivoChem LLC
CASRN 93718-83-3
Amount 100 mg
Quantity options 10 mg 250 mg 25 mg 50 mg 5 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V4941CAS #:93718-83-3Purity >=98%

Description: NSC-95397 is a novel, potent, and selective CDC25B inhibitor which inhibits influenza A virus replication in dose-dependent fashion. NSC 95397 also inhibits mitogen-activated protein kinase phosphatase-1 (MKP-1) and suppresses proliferation and induces apoptosis in colon cancer cells through MKP-1 and ERK1/2 pathway.NSC95397 prevents the CtBP1-Protein Partner Interaction and CtBP1-Mediated Transcriptional Repression. NSC-95397 triggers apoptosis of tumor cells and is thus considered for the treatment of malignancy. NSC 95397 is a Cdc25 dual specificity phosphatase inhibitor (Ki=32 nM (Cdc25A), 96 nM (Cdc25B), 40 nM (Cdc25C); IC50=22.3 nM (human Cdc25A), 56.9 nM (human Cdc25C), 125 nM (Cdc25B)).

References: Int J Mol Sci. 2018 May 31; 19(6). pii: E1625.

NSC-95397

Name: NSC-95397
CAS#: 93718-83-3
Chemical Formula: C14H14O4S2
Exact Mass: 310.0334
Molecular Weight: 310.382
Elemental Analysis: C, 54.18; H, 4.55; O, 20.62; S, 20.66
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Technical Information
Synonym: NSC-95397; NSC95397; NSC 95397
Chemical Name: 2, 3-Bis(2-hydroxyethylsulfanyl)naphthalene-1, 4-dione
InChi Key: MAASHDQFQDDECQ-UHFFFAOYSA-N
InChi Code: InChI=1S/C14H14O4S2/c15-5-7-19-13-11(17)9-3-1-2-4-10(9)12(18)14(13)20-8-6-16/h1-4, 15-16H, 5-8H2
SMILES Code: O=C1C(SCCO)=C(SCCO)C(C2=C1C=CC=C2)=O

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 mg
Available: In stock
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