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WEHI-345

WEHI-345

Item no.	V28191-50mg
Manufacturer	InvivoChem LLC
CASRN	1354825-58-3
Amount	50 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V28191CAS #:1354825-58-3Purity >=98% Description: WEHI-345 is a novel, potent and selective RIPK2 inhibitor which has an IC50 of 0.13 uM and shows NOD signalling events yet prevents inflammatory cytokine production. WEHI-345 delays RIPK2 ubiquitylation and NF-kappaB activation downstream of NOD engagement. Despite only delaying NF-kappaB activation on NOD stimulation, WEHI-345 prevents cytokine production in vitro and in vivo and ameliorates experimental autoimmune encephalomyelitis in mice. References: A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production. Nat Commun. 2015 Mar 17; 6:6442.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 mg

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Delivery expected until 10/2/2025

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