RUSC2 Antibody

Primary Antibodies

RUSC2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

RUSC2 Antibody: RUSC2, also known as Iporin, shares with the related protein RUSC1 a common domain structure of RUN, leucine zipper and SH3 domain in addition to over 30% amino acid identity. RUSC2 is a rab1-interacting protein that also interacts with GM130, another rab1-interacting protein. RUSC2 interacts with specific rab1 isoforms with different rab-binding specificity. It has been suggested that RUSC2 may function as a link between the targeting of ER derived vesicles triggered by the rab1 GTPase and a signaling pathway composed of proteins containing SH3 and/or poly-proline regions.

Trial Size

55741719

1 mg/mL

RUSC2 antibody can be used for detection of RUSC2 by immunohistrochemistry at 5 μ g/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.

At least three isoforms are known to exist; this antibody will only detect the longest isoform. This antibody is predicted to not cross-react with RUSC1.

Polyclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.