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SMYD3-IN-1

SMYD3-IN-1

Item no.	HY-128352-100mg
Manufacturer	MedChem Express
CASRN	2095160-79-3
Amount	100 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 ea 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	98.01
Citations	[1]Huang C, et al. Discovery of Irreversible Inhibitors Targeting Histone Methyltransferase, SMYD3. ACS Med Chem Lett. 2019 May 23;10(6):978-984.
Smiles	O=C(N1[C@H](C)CN(C(C2=CC=C3C(Cl)=CC(C4=CC=C(C5(N)CC5)C=C4)=NC3=C2)=O)CC1)OCCC
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Histone Methyltransferase
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	507.02
Product Description	SMYD3-IN-1 (compound 29) is an irreversible and selective inhibitor of SMYD3 (SET and MYND domain containing 3), with an IC50 of 11.7 nM[1].
Manufacturer - Research Area	Cancer
Solubility	DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Epigenetics
Isoform	SMYD3
Clinical information	No Development Reported

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HY-128352-100mg-safety-datasheet.pdf