« Back
Home /
IACS-8803 (disodium)

IACS-8803 (disodium)

Item no.	HY-130115A-50mg
Manufacturer	MedChem Express
CASRN	2243079-36-7
Amount	50 mg
Quantity options	10 mM/1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	99.97
Citations	[1]Ager CR, et al. Discovery of IACS-8803 and IACS-8779, potent agonists of stimulator of interferon genes (STING) with robust systemic antitumor efficacy. Bioorg Med Chem Lett. 2019 Oct 15;29(20):126640.
Smiles	NC1=NC=NC2=C1N=CN2[C@H]3[C@H](F)[C@H](O[P@@]4(S[Na])=O)[C@@H](CO[P@](O[C@@H]5[C@H](O)[C@@H](CO4)O[C@H]5N(C=N6)C7=C6C(N)=NC=N7)(S[Na])=O)O3
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	STING
Shipping Temperature	Blue Ice
Storage Conditions	-20°C (Powder, stored under nitrogen, away from moisture)
Molecular Weight	736.50
Product Description	IACS-8803 disodium is a highly potent cyclic dinucleotide STING agonist. IACS-8803 disodium has a robust systemic antitumor efficacy[1].
Manufacturer - Research Area	Cancer
Solubility	DMSO: ≥ 100 mg/mL\|H2O: 56.67 mg/mL (ultrasonic)
Manufacturer - Pathway	Immunology/Inflammation
Clinical information	No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

HY-130115A-50mg-safety-datasheet.pdf