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Raloxifene 6-Monomethyl Ether

Raloxifene 6-Monomethyl Ether

Item no.	HY-135584-1ea
Manufacturer	MedChem Express
CASRN	178451-13-3
Amount	1 ea
Quantity options	100 mg 1 ea
Category	Inhibitors & Compound Libraries Small Molecules
Type	Molecules
Specific against	other
Citations	[1]Chang YH, et al. Computational study of estrogen receptor-alpha antagonist with three-dimensional quantitative structure-activity relationship, support vector regression, and linear regression methods. Int J Med Chem. 2013;2013:743139.
Smiles	O=C(C1=C(C2=CC=C(O)C=C2)SC3=CC(OC)=CC=C31)C4=CC=C(OCCN5CCCCC5)C=C4
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Metabolism-protein/nucleotide metabolism
Manufacturer - Targets	Estrogen Receptor/ERR
Shipping Temperature	Room temperature
Molecular Weight	487.61
Product Description	Raloxifene 6-Monomethyl Ether (Compound 7) is a Raloxifene derivative that inhibits estrogen receptor α. Raloxifene 4-Monomethyl Ether inhibits MCF-7 cells with an IC50 of 250 nM and a pIC50 of 6.6[1].
Manufacturer - Research Area	Endocrinology
Solubility	10 mM in DMSO
Manufacturer - Pathway	Vitamin D Related/Nuclear Receptor
Clinical information	No Development Reported

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