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(S,R,S)-AHPC-C6-PEG3-butyl-N3 European Partner

Item no. HY-151791-50mg
Manufacturer MedChem Express
CASRN 2300155-90-0
Amount 50 mg
Quantity options 1 ea 50 mg
Category
Type Inhibitors
Specific against other
Citations [1]Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789.
Smiles [N-]=[N+]=NCCCCCCOCCOCCOCCCCCC(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)=O)=O
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Shipping Condition Room temperature
Available
Manufacturer - Type
Reference compound
Manufacturer - Applications
Cancer-programmed cell death
Manufacturer - Targets
ADC Linker; E3 Ligase Ligand-Linker Conjugates
Shipping Temperature
Room temperature
Molecular Weight
757.98
Product Description
(S, R, S)-AHPC-C6-PEG3-butyl-N3 is a click chemistry reagent containing an azide group. (S, R, S)-AHPC-C6-PEG3-butyl-N3 serves as crosslinker-E3 ligase ligand conjugate, Click reactive protein degrader building block for PROTAC research, Template for synthesis of targeted protein degrader, VH032 conjugate[1]. (S, R, S)-AHPC-C6-PEG3-butyl-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Manufacturer - Research Area
Others
Solubility
10 mM in DMSO
Manufacturer - Pathway
Antibody-drug Conjugate/ADC Related; PROTAC
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 mg
Available: In stock
available

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