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INSM1 (insulinoma-associated 1)

INSM1 (insulinoma-associated 1)

Item no.	18-003-42133
Manufacturer	GENWAY
Amount	0.1 mg
Category	Oncology Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Antibodies Immunohistochemistry Western Blot Endocrine Regulation of Lipid Metabolism Primary Antibodies By Organ Lung Cancer
Type	Antibody
Applications	WB, IHC
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GWB-6EE1CD
Similar products	18-003-42133
Available
Genway ID:	GWB-6EE1CD
Antigen Specificity:	Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human INSM1.
ELISA Titre:	1:312500
Note:	Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity. Insulinoma-associated 1 (INSM1) gene is intronless and encodes a protein containing both a zinc finger DNA-binding domain and a putative prohormone domain. This gene is a sensitive marker for neuroendocrine differentiation of human lung tumors.
Function:	May be associated with the transformation of neuroendocrine cells.
Subcellular Location:	Nucleus (Potential).
Tissue Specificity:	Several tumor cell lines of neuroendocrine origin including pheochromocytoma medullary thyroid carcinoma insulinoma pituitary tumor and small cell lung carcinoma. Not found in any of the normal tissues tested.
Similarity:	Contains 5 C2H2-type zinc fingers. Summary: Insulinoma-associated 1 (INSM1) gene is intronless and encodes a protein containing both a zinc finger DNA-binding domain and a putative prohormone domain. This protein is a sensitive marker for neuroendocrine differentiation of human lung tumors. Breslin. M. B. . et al. . (2003) J. Biol. Chem. 278(40). 38991-7.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 9/25/2025

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