TD-106

Item no.	HY-114406-25mg
Manufacturer	MedChem Express
CASRN	2250288-69-6
Amount	25 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 25 mg 50 mg 5 mg
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.81
Citations	[1]Kim SA, et al. A novel cereblon modulator for targeted protein degradation. Eur J Med Chem. 2019 Mar 15;166:65-74.
Smiles	NC1=CC=CC(N=NN2C3CCC(NC3=O)=O)=C1C2=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Ligands for E3 Ligase
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture and light)
Molecular Weight	273.25
Product Description	TD-106 is a cereblon (CRBN) modulator, which can be used for targeted protein degradation. BRD4 PROTACs with TD-106 induce BRD4 degradation[1].
Manufacturer - Research Area	Cancer
Solubility	DMSO: ≥ 125 mg/mL
Manufacturer - Pathway	PROTAC
Isoform	Cereblon
Clinical information	No Development Reported

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HY-114406-25mg-safety-datasheet.pdf