Mediator Complex Subunit 17 (MED17) Antibody

Mediator Complex Subunit 17 (MED17)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor (TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.

PBS containing 0.09% sodium azide.

MED17

Purified through a protein A column, followed by peptide affinity purification.