Anti-Transglutaminase 2/TGM2 Antibody Picoband®

Primary Antibodies

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

77329 MW

Immunohistochemistry (Paraffin-embedded Section), 0.5-1?g/ml, Human, By Heat

Immunocytochemistry , 0.5-1?g/ml, Human, -
Western blot, 0.1-0.5?g/ml, Human, Rat

Protein-glutamine gamma-glutamyltransferase 2

Tissue transglutaminase, also called TGC, is a 78-kDa, calcium dependent enzyme of the protein-glutamine gamma-glutamyltransferases family. By fluorescence in situ hybridization (FISH), this gene is mapped in 20q11.23. Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease.

Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.

Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.

Amino Acid Metabolism, Amino Acids, Apoptosis, Associated Proteins, Autoimmune, Calcium Binding Proteins, Calcium Signaling, Cancer, Cell Biology, Immune System Diseases, Immunology, Intracellular, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction, Signaling Pathway

Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.

Boster Bio Anti-Transglutaminase 2/TGM2 Antibody catalog # PA2153. Tested in IHC, ICC, WB applications. This antibody reacts with Human, Rat.