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HSD17B1 Polyclonal Antibody

HSD17B1 Polyclonal Antibody

Item no.	E-AB-16497-60
Manufacturer	Elabscience
Amount	60 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Oncology Food Safety Hormones Metabolism Diabetes Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies By Organ Breast Cancer Testicular & Prostate Cancer Uterine, Ovarian & Cervical Cancer
Type	Antibody Polyclonal
Applications	WB, IHC
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	17 beta HSD 1, 17 beta hydroxysteroid dehydrogenase type 1, 17-beta-HSD 1, 17-beta-hydroxysteroid dehydrogenase type 1, 20 alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, DHB1, E17KSR, E2DH, EDH17B1, EDH17B2, EDHB17, Estradiol 17 beta dehydrogenase 1, Estradiol 17-beta-dehydrogenase 1, HSD17, HSD17B1, Hydroxysteroid (17 beta) dehydrogenase 1, MGC13814, Placental 17 beta hydroxysteroid dehydrogenase, Placental 17-beta-hydroxysteroid dehydrogenase, SDR28C1, Short chain dehydrogenase/reductase family 28CE, member 1
Similar products	HSD17B1, E17KSR, EDH17B1, EDH17B2, EDHB17, Estradiol 17-beta-dehydrogenase 1, 17-beta-hydroxysteroid dehydrogenase type 1, 20 alpha-hydroxysteroid dehydrogenase, E2DH, Placental 17-beta-hydroxysteroid dehydrogenase, member 1, HSD17, SDR28C1, DHB1, 17 beta HSD 1, 17 beta hydroxysteroid dehydrogenase type 1, 17-beta-HSD 1, 20-alpha-HSD, Estradiol 17 beta dehydrogenase 1, Placental 17 beta hydroxysteroid dehydrogenase, Short chain dehydrogenase/reductase family 28CE, Hydroxysteroid (17 beta) dehydrogenase 1, MGC13814
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	HSD17B1
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	35kDa
Research Areas	Cancer, Metabolism, Neuroscience, Signal transduction
Background	Hydroxysteroid (17-beta) dehydrogenase 1 catalyzes the final step in the formation of estradiol and testosterone from estrone and androstenedione, respectively. Ovarian granulosa cells and breast tissue both express HSD17B1. Other tissues that express HSD17B1 include testis, placenta, uterus, prostate and adipose tissue. HSD17B1 functions as a homodimer and prefers NADP(H) over NAD(H) for oxidation and reduction. The gene encoding human HSD17B1 maps to chromosome 17q12-q21. The importance of HSD17B1 to estradiol production suggests the specific inhibition of HSD17B1 may aid in breast cancer therapy.
Concentration	0.5 mg/mL
Buffer	PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method	Affinity purification
Recommended Dilution	WB 1:500-1:2000; IHC 1:50-1:200
Santa Cruz #	sc-26964, sc-26963, sc-26965, sc-32872, sc-32871
Abbreviation	HSD17B1
Clonality	Polyclonal
Immunogen	Synthetic peptide of human HSD17B1
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.