Aldo-Keto Reductase Family 1 Member C3 (AKR1C3) Antibody

Aldo-Keto Reductase Family 1 Member C3 (AKR1C3)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha, 11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

PBS containing 0.09% sodium azide.

AKR1C3

Purified through a protein A column, followed by peptide affinity purification.