RBBP7 Polyclonal Antibody

47kDa/52kDa

This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene.

PBS with 0.02% sodium azide and 50% glycerol pH 7.4

WB 1:500 - 1:2000 IF 1:50 - 1:100 IP 1:50 - 1:200