Comparison

OxiSelect™ Oxidative DNA Damage Quantitation Kit (AP sites)

Item no. STA-324
Manufacturer Cell Biolabs
Amount 50 assays
Category
Type Kit
Specific against other
ECLASS 10.1 32161090
ECLASS 11.0 32161090
UNSPSC 41116126
Shipping Condition Room temperature
Available
Manufacturer - Category
Kit
Shipping Temp
Room Temperature
Storage Temp
Upon receipt, aliquot and store both the Reduced DNA and ARP-DNA Standards at -20°C to avoid multiple freeze/thaw cycles. Store all other components at 4°C.
Additional Information
Detect as few as 4-40 AP sites in 10^5 bp DNA 
Suitable for use with cells or tissues
Oxidized and reduced DNA standards included for absolute quantitation
LMO Content
None
Product Line
Oxidative Stress/Damage
Product Classification
Oxidative Stress/ Damage->DNA / RNA Damage and Repair->AP Sites Quantitation Kit
Description
DNA damage can manifest in the formation of apurinic or apyrimidinic (AP or abasic) sites. Such spontaneous base loss in mammalian cells has been estimated at between 50, 000 and 200, 000 sites per day. Unrepaired abasic sites can inhibit transcription and may be mutagenic. Our OxiSelect™ Oxidative DNA Damage Quantitation Kit provides a simple, user-friendly method for the quantitaiton DNA damage in the form of abasic sites. The assay uses an Aldehyde Reactive Probe (ARP) to specifically react with an aldehyde group on the open ring of the AP site. This allows the AP site to be labeled with Biotin, followed by detection with Streptavidin-Enzyme conjugate.
Detection Method
Colorimetric
UNSPSC
41116100

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 assays
Available: In stock
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