Mouse Anti-Human PODXL Clone GB6D9C11 mAb

Antibodies

Podocalyxin is the major sialoprotein in the glycocalyx of glomerular podocytes, endothelial cell membranes contain podocalyxin. By immunoelectron microscopy podocalyxin was localized on the luminal membrane domain of endothelial cells, in a patchy distribution. The presence of podocalyxin was confirmed in SDS extracts of lung tissue by immunoblotting. It was concluded that (a) podocalyxin is a widespread component of endothelial plasma membranes, (b) it is restricted to the luminal membrane domain, and (c) it is distributed unevenly on the endothelial cell surface.

Membrane protein fraction of isolated human glomeruli

Centrifuge vial prior to opening. Add sterile distilled water to the vial to fully solubilize the antibody to a concentration > 0.5 mg/ml.