Comparison

Rabbit Anti-Human VEGFR2/KDR Biotin Affinity Purified pAb

Item no. CS-CPV113
Manufacturer Cell Sciences
Amount 50 ug
Category
Type Antibody Polyclonal
Applications ELISA
Specific against Human (Homo sapiens)
Host Rabbit
Conjugate/Tag Biotin
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products VEGFR2, FLK1, CD309, VEGFR, fetal liver kinase-1, protein-tyrosine kinase receptor Flk-1, soluble VEGFR2, tyrosine kinase growth factor receptor, vascular endothelial growth factor receptor 2, fetal liver kinase 1
Available
Manufacturer - Category
Antibodies
Storage Conditions
The lyophilized antibody is stable at room temperature for up to one month. On receipt, store lyophilized antibody at -20C. Reconstituted antibody is stable for at least six weeks at 2-4C or for more than six months stored in working aliquots at -20C. Avoid repeated freeze-thaw cycles.
Description
sKDRD1-7 is produced as a non-chimeric protein in a monomeric form. The soluble receptor protein consists of all 7 extracellular domains, which contain all the information necessary for high affinity ligand binding. The receptor monomers have a mass of approximately 116 kDa. Endothelial cells express three different vascular endothelial growth factor (VEGF) receptors, belonging to the family of receptor tyrosine kinases (RTKs). They are named VEGFR-1 (Flt-1), VEGFR-2 (KDR/Flk-1), VEGFR-3 (Flt-4). Their expression is almost exclusively restricted to endothelial cells, but VEGFR-1 can also be found on monocytes. All VEGF-receptors have seven immunoglobulin-like extracellular domains, a single transmembrane region and an intracellular split tyrosine kinase domain. VEGFR-2 has a lower affinity for VEGF than the Flt-1 receptor, but a higher signaling activity. Mitogenic activity in endothelial cells is mainly mediated by VEGFR-2 leading to their proliferation. The binding of VEGF165 to VEGFR-2 is dependent on heparin.
Formulation
Lyophilized from PBS + 50x BSA + 0.02% sodium azide. Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only.
Immunogen
Recombinant human soluble KDR protein (D1-7)
Purification
Protein A purified
Reconstitution
Centrifuge vial prior to opening. Add sterile distilled water to the vial to fully solubilize the antibody to a concentration of 0.1-1.0 mg/ml.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
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