Rabbit Anti-Human SOCS6 Clone Poly6155 pAb

The SOCS6 (suppressor of cytokine signaling-6) protein is a 59 kD cytoplasmic protein that contains a SOCS box and an SH2 domain. SOCS6 has been implicated as an inhibitor of IR signaling and has been shown to mediate cytokine-induced insulin resistance. SOCS6 is induced by erythropoietin and GM-CSF. The SOCS6 protein has been shown to interact with elongins B and C, and the insulin receptor. This protein forms a complex with IRS-4, IRS-2, and PI3K. The Poly6155 antibody recognizes the N-terminal region of human SOCS6 and has been shown to be useful for Western blot.

Recombinant (partial), N-terminal