Rabbit Anti-Human LGALS3/Galectin-3 Clone Poly6132 pAb

Galectin 3 (also known as galactose-specific lectin 3 and Mac-2 antigen) is a 32 kD member of the galaptin (S-lectin) family, BH-1, that contains carbohydrate recognition domains. This protein forms homo- and hetero-dimers and localizes to the nucleus or cytoplasm depending on proliferation state. Galectin 3 has been shown to modulate allergic reactions and regulate mRNA splicing activity, cell cycle control, and cell adhesion. The expression of galectin 3 can be increased by acetylated LDL, oxidized LDL, and Runx2. Galectin 3 can be modified by phosphorylation and acetylation and has been shown to interact with IgE, galactose, casein kinase I, laminin, mucin, a-galactoside residues of cell surface, matrix glycoproteins, and some intracellular proteins. The Poly6132 antibody recognizes human and mouse galectin 3 and has been shown to be useful for Western blot.

Recombinant human (partial), amino acids 151-251.