Rabbit Anti-Human Cathepsin D pAb

Antibodies

44.6 kDa

Cathepsin D (CTSD) is a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease.

Antisera, Purified IgG by Ammonium Sulfate Fractionation