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Mouse Anti-Human CD41a Clone VM16a mAb

Mouse Anti-Human CD41a Clone VM16a mAb

Item no.	CS-MON1144
Manufacturer	Cell Sciences
Amount	1 ml
Category	Neuroscience Aging & Neurological Disorders Neural Adhesion Molecules Antibodies Cell Biology Cell Movement Cell Adhesion Flow Cytometry Immunofluorescence Primary Antibodies
Type	Antibody Monoclonal
Applications	FC
Clone	VM16a
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Similar products	HPA3, alpha subunit, CD41, CD41B, GP2B, GPIIb, GTA, platelet fibrinogen receptor, platelet-specific antigen BAK, GPalpha IIb, integrin alpha-IIb, platelet membrane glycoprotein IIb
Available
Storage Conditions	Store antibody at 2-8C until expiration date.
Description	Mouse Anti-Human CD41a Clone VM16a monoclonal antibody recognizes the intact platelet GPIIb/IIIa complex (alphaIIb/beta3). It does not bind to dissociated GPIIb or GPIIIa. The antibody reacts with human platelets and megakaryocytes. The apparent molecular weight of GPIIIa, GPIIb alpha chain, and GPIIb beta chain under reducing conditions are as follows: GPIIIa: 110 kDa, GPIIb alpha chain: 125 kDa, GPIIb beta chain: 25 kDa. The antibody does not bind to platelets from patients with Glanzmann thrombasthenia and does not recognize the vitronectin receptor, which contains GPIIIa as a beta subunit. VM16a inhibits platelet Fc-receptor dependent reactions due to the proposed topographical association of the platelet Fc-receptor and the glycoprotein IIb-IIIa complex.
Formulation	1 ml lyophilized purified IgG solution in PBS
Purification	Ammonium sulfate + DEAE-cellulose, gradient elution
Reconstitution	Centrifuge vial prior to opening. Add 1 ml sterile distilled water to the vial to fully solubilize the antibody to a concentration of 0.2 mg/ml. Sufficient for 100 tests.
Specificity	Human CD41a, (Recognizes the intact platelet GPIIb/IIIa complex (alphaIIb/beta3))
Concentration	Approx. 0.2 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 ml

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Delivery expected until 1/29/2026

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