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Mouse Anti-Human IGF-IIR (Clone MEM-238) mAb

Mouse Anti-Human IGF-IIR (Clone MEM-238) mAb

Item no.	CS-MON2064
Manufacturer	Cell Sciences
Amount	100 ug
Category	Oncology Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Antibodies By Cell Type Carcinoma Sarcoma Cell Biology Cell Culture Cytokines Endocrine Regulation of Lipid Metabolism Primary Antibodies
Type	Antibody Monoclonal
Clone	MEM-238
Specific against	Human (Homo sapiens)
Isotype	IgG1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Similar products	M6PR, CD222, CIMPR, M6P-R, MPR1, MPRI, cation-independent mannose-6 phosphate receptor, CI Man-6-P receptor, CI-MPR, 300 kDa mannose 6-phosphate receptor, MPR 300, IGF-II receptor, M6P/IGF2 receptor, M6P/IGF2R, cation-independent mannose-6-phosphate receptor, insulin-like growth factor II receptor
Available
Manufacturer - Category	Antibodies
Storage Conditions	Store antibody at 2-8C until expiration date.
Application Notes	The optimal concentration should be determined by the user for each specific application.
Description	The protein encoded by this gene is a receptor for both, insulin-like growth factor 2 (IGF2) and mannose 6-phosphate (M6P). The IGF2 and M6P binding sites are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of IGF2.
Formulation	100 ug in solution (PBS containing 15 mM sodium azide, pH 7.4).
Immunogen	Vaccinia-M6PR/iGFIIR
Specificity	The antibody MEM-238 recognizes an epitope between domains 2 and 5 of IGF2R, a ubiquitously expressed 250 kDa multifunctional type I transmembrane protein. The majority of the protein is found in the late endosomal/ prelysosomal compartment, 5-10% in the plasma membrane and the truncated (220 kDa) form of the protein is present in human and bovine serum

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 10/2/2025

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