Comparison

Mouse Anti-Human Endoglin/CD105 Clone MEM226 mAb

Item no. CS-MON2070
Manufacturer Cell Sciences
Amount 100 ug
Category
Type Antibody Monoclonal
Applications FC
Clone MEM-226
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2a
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Similar products CD105, END, HHT1, FLJ41744, ORW, ORW1, CD105 antigen, OTTHUMP00000022221
Available
Manufacturer - Category
Antibodies
Storage Conditions
Store undiluted antibody at 2-8C for 12 months. Do not freeze. Avoid prolonged exposure to light.
Description
CD105 (Endoglin) is a homodimeric transmembrane glycoprotein serving in presence of TGFbetaR-2 as a receptor for TGFbeta-1 and TGFbeta-3. CD105 is highly expressed on endothelial cells and promotes angiogenesis during wound healing, infarcts and in a wide range of tumors and its gene expression is stimulated by hypoxia. CD105 prevents apoptosis in hypoxic endothelial cells and also antagonises the inhibitory effects of TGFbeta-1 on vascular endothelial cell growth and migration. Normal cellular levels of CD105 are required for formation of new blood vessels.
Formulation
Storage Buffer: PBS containing BSA and 15 mM sodium azide (pH 7.4). Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only. Suitable for 100 tests

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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