Mouse Anti-Human Collagen-4 Clone MC4-HA mAb

Store antibody at 2-4C until expiration date. Avoid repeated freeze-thaw cycles .

The extent of expression of the basement membrane component type IV collagen may be correlated with the degree of differentiation of basement membrane producing neoplasms. Neoplastic cells of invasive carcinomas often lack a continuous basement membrane. In diagnostic histopathology antibodies to type IV collagen may help to distinguish between non-invasive (benign or, in situ ) and invasive lesions. Furthermore the antibody is important in the differential diagnosis of bullous lesions in dermatopathology. In, in vitro, studies with endothelial cells and smooth muscle cells the antibody is helpful in detection of production collagen type IV.

Human collagen IV

Centrifuge vial prior to opening . Reconstitute with 1 ml sterile distilled water and add preservative if preferred.