Mouse Anti-Proximal Nephrogenic Renal Antigen Clone PN-15 mAb

Antibodies

PN-15 reacts with a glycoprotein of 200 kD (gp200), present in proximal renal tubules. The antigen is carbohydrate in nature and retained in formalin fixed paraffin embedded tissues. Other nornal tissues that display the antigen include breast, parathyroid glands and epididymis. Among renal carcinomas 93% of primary and 84% of metastatic carcinomas are positive. Relatively few other tumor types are postivie: breast cancers, teratocarcinomas and parathyroid adenomas. Protease digestion prior to antibody incubation enhances staining of tissue sections. Source: A BALB/c mouse was immunized with renal cortical tissue extract. Splenocytes were fused with mouse myeloma SP2/0Ag14 cells.

100 ug/ml