Rabbit Anti-Mouse Laminin pAb

Stable for 2 months when stored undiluted at 2-4C or in working aliquots at -20C for longer storage. Avoid repeated freeze-thaw cycles .

Rabbit Anti-Laminin polyclonal antibody. Laminin is a non-collagenous protein of basement membranes. This glycoprotein has a molecular weight of about 900 kDa. By rotary shadowing it has a cross-like shape, consisting of one long arm, (400 kDa) and three short arms (200 kDa). Antibodies to laminin localize exclusively in basement membranes. Laminin is found throughout the basement membrane, but the reaction with the antibodies to Laminin is more intense in the lamina lucida, the part of the basement membrane adjacent to the cell membrane. Laminin binds to type IV collagen, a component exclusively localized in the basement membrane. Laminin has been shown to play a role in cell adhesion and attachment, in vivo, and, in vitro .

Isolated from EHS-mouse sarcoma. Antigen location: basement membrane