Rabbit Anti-Rat CXCL12/SDF-1 beta pAb

2-4C for short term storage or -20C in small aliquots for long term storage. Avoid repeated freeze-thaw cycles.

SDF-1 beta (stromal cell-derived factor-beta), also known as pre-B-cell growth-stimulating factor (PBSF), is a 70-amino acid CXC chemokine originally cloned from a bone marrow stromal cell line. Targeted deletion of SDF-1 gene resulted in defects of B-cell lymphopoiesis and bone marrow myelopoiesis in mice. SDF-1 has been shown to be chemotactic for lymphocytes. In addition, SDF-1 was recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV-1 entry into T-cells. SDF-1 binding to CXCR4 inhibits HIV-1 entry. This polyclonal antibody, which reacts with both mouse and rat SDF-1beta, was generated using, E. coli, -expressed mouse SDF-1beta as an immunogen.

Recombinant mouse SDF-1 beta

Centrifuge vial prior to opening. Reconstitute to 1 mg/ml by adding 200 ul water.