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Recombinant Human proIGF2 (aa 1-104) Receptor Grade

Recombinant Human proIGF2 (aa 1-104) Receptor Grade

Manufacturer	Cell Sciences
Category	Oncology Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite By Cell Type Carcinoma Sarcoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Endocrine Regulation of Lipid Metabolism
Type	Proteins
Specific against	Human
Format	Lyophilized
Amount	100 ug
Host	E.coli
Item no.	CS-AZU100
Targets	IGF2, IGF1, INS
eClass 6.1	34160400
eClass 9.0	42020190
Available
Biological Activity	Stimulation of protein synthesis in rat L6 myoblasts.
Description	The IGF-II gene encodes a single transcript which results in an 156 amino acid protein, including an 89 amino acid E-domain. ProIGF-II contains sites of O-linked glycosylation. ProIGF-II is converted to mature IGF-II by sequential cleavage after amino acids 104, 87 and 67. Differential glycosylation and cleavage within the E-domain can therefore result in multiple proIGF-II isoforms. The proIGF-II proteins make up 10-20% of circulating IGF-II. ProIGF-II proteins are secreted by some tumor cell lines and levels are elevated in non-islet cell tumor hypoglycemia.
Molecular Weight	11.949 kDa – confirmed by Mass Spectometry.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

CS-AZU100.pdf

CS-AZU100-datasheet.pdf

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Amount: 100 ug

available

Delivery expected until 5/23/2024