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Recombinant Human Cytokeratin 20

Recombinant Human Cytokeratin 20

Manufacturer	Cell Sciences
Category	Oncology Peptides & Proteins Recombinant Proteins Cell Biology Cytoskeleton Intermediate filaments By Organ Bladder Cancer Gastric Cancer
Type	Proteins
Specific against	Human
Amount	20 ug
Host	E.coli
Item no.	CS-CRC179B
Targets	KRT20
eClass 6.1	34160400
eClass 9.0	42020190
Available
Description	KRT20 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21.
Endotoxin Level	< 0.1 ng/ug of KRT20
Formulation	Lyophilized from a sterile filtered solution containing 30 mM Tris-HCl, pH 8.0 + 9.5 M urea + 2 mM DDT + 2 mM EDTA + 10 mM methylammonium chloride
Molecular Weight	48.6 kDa
Reconstitution	Centrifuge vial prior to opening. First add sterile water to the vial to fully solubilize the protein to a concentration not less than 100 ug/ml. After complete solubilization of the protein, it can be further diluted to other aqueous solutions.
Storage and Stability	Store lyophilized protein at -20C to -80C. Reconstituted protein is stable for 1 week, at 2-4C. For long term storage, aliquot and store at -20C to -80C with a carrier protein (0.1% HSA or BSA) as a stabilizer. Please note that the addition of any carrier protein into this product may produce unwanted endotoxin. This depends upon the particular application employed. Avoid repeated freeze-thaw cycles.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.