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Recombinant Human ERK1 Active

Recombinant Human ERK1 Active

Manufacturer	Cell Sciences
Category	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Signaling Peptides & Proteins Recombinant Proteins Neuronal Cell Markers
Type	Proteins
Specific against	Human
Amount	5 ug
Item no.	CS-CRE106A
Targets	MAPK3
eClass 6.1	34160400
eClass 9.0	42020190
Available
Description	Recombinant full-length, tag free, human ERK1 was expressed in Sf9 cells and activated by active MEK1, in vitro . ERK1 is a protein serine/threonine kinase that is a member of the extracellular signal-regulated kinases (ERKs) which are activated in response to numerous growth factors and cytokines. Activation of ERK1 requires both tyrosine and threonine phosphorylation that is mediated by MEK. ERK1 is ubiquitously distributed in tissues with the highest expression in heart, brain and spinal cord. Activated ERK1 translocates into the nucleus where it phosphorylates various transcription factors (e.g. Elk-1, c-Myc, c-Jun, c-Fos, and C/EBP beta).
Formulation	Recombinant protein stored in 50 mM Tris-HCl, pH 7.5 + 150 mM NaCl + 0.25 mM DTT + 0.1 mM EGTA + 0.1 mM EDTA + 0.1 mM PMSF + 25% glycerol.
Molecular Weight	ca.44 kDa
Storage and Stability	Shipped on dry ice. Store product frozen at or below -80C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated freeze-thaw cycles.
Specificity	383 nmol/min/mg

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.