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Recombinant Human IGF-2

Recombinant Human IGF-2

Item no.	CS-CRI502C
Manufacturer	Cell Sciences
Amount	1.0 mg
Category	Oncology Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite By Cell Type Carcinoma Sarcoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Endocrine Regulation of Lipid Metabolism
Type	Proteins
Specific against	Human (Homo sapiens)
Host	E.coli
Purity	Purity determined by 1) UV spectroscopy at 280 nm, 2) RP-HPLC calibrated against a known standard, and 3) quantitation against a known standard via reducing and non-reducing SDS-PAGE gels.
Sequence	AYRPSETLCG GELVDTLQFV CGDRGFYFSR PASRVSRRSR GIVEECCFRS CDLALLETYC ATPAKSE
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	IGF-II, C11orf43, FLJ22066, FLJ44734, INSIGF, pp9974, insulin-like growth factor II, insulin-like growth factor type 2, PP1446, somatomedin A, somatomedin-A, OTTHUMP00000220677, putative insulin-like growth factor II associated protein
Available
Manufacturer - Category	Biomolecules
Storage Conditions	Lyophilized recombinant human IGF-II, although stable at room temperature, should be stored desiccated at -20C. Upon reconstitution, recombinant human IGF-II should be stored in working aliquots at -20C. For long term storage, it is recommended that a carrier protein (0.1% HSA or BSA) should be added to the solution. This depends upon the particular application employed. Avoid repeated freeze-thaw cycles.
Molecular Weight	7.5 kDa
Description	Insulin like Growth Factor II, IGF-II, is a major growth hormone made by Theca cells during gestation. While IGF-II is known to engage the IGF-I receptor (IGF1R) to mediate embryonic growth, IGF-II is also known to bind the IGF-II receptor (IGF2R), which is thought to be signaling dead receptor that acts as a sink by binding up free IGF-II. Recombinant Human IGF-II is non-glycosylated protein containing 67 amino acids and having a MW = 7.5 kDa.
Formulation	Sterile filtered white lyophilized powder with no additives
Reconstitution	Centrifuge vial prior to opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Biological Activity	The activity is determined by the dose dependent proliferation of FDC-P1 cells and is typically 1.5-6 ng/ml.
Endotoxin Level	Less than <0.01 ng/ug or <0.1 EU/ug.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1.0 mg

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Delivery expected until 9/11/2025

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