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Recombinant Human LIF

Recombinant Human LIF

Item no.	CS-CRL126C
Manufacturer	Cell Sciences
Amount	1 mg
Category	Oncology Metabolism Diabetes Glucose Homeostasis Peptides & Proteins Recombinant Proteins Obesity By Organ Skin Cancer Heart & Blood Cancer
Type	Proteins
Specific against	Human (Homo sapiens)
Host	E.coli
Purity	>98% by SDS-PAGE and HPLC analyses.
Sequence	SPLPITPVNA TCAIRHPCHN NLMNQIRSQL AQLNGSANAL FILYYTAQGE PFPNNLDKLC GPNVTDFPPF HANGTEKAKL VELYRIVVYL GTSLGNITRD QKILNPSALS LHSKLNATAD ILRGLLSNVL CRLCSKYHVG HVDVTYGPDT SGKDVFQKKK LGCQLLGKYK QIIAVLAQAF
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	LIF, CDF, HILDA, MLPLI, Leukemia inhibitory factor, Melanoma-derived LPL inhibitor, D-FACTOR, Differentiation- stimulating factor, Emfilermin, DIA.
Available
Manufacturer - Category	Biomolecules
Storage Conditions	This lyophilized preparation is stable at 2-4C, but should be kept desiccated at -20C for long term storage. Upon reconstitution, the preparation is stable for up to one week at 2-4C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20C to -80C. Avoid repeated freeze/thaw cycles.
Molecular Weight	19.7 kDa
Description	Leukemia Inhibitory Factor (LIF) is a lymphoid factor which promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. LIF has a number of other activities including cholinergic neuron differentiation, control of stem cell pluripotency, bone and fat metabolism, mitogenesis of certain factor dependent cell lines and promotion of megakaryocyte production, in vivo .
Formulation	Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4
Specificity	2 x 108 IU/mg, where 50 units is defined as the amount of rHuLIF required to induce differentiation in 50% of the M1 colonies in 1ml agar cultures.
Biological Activity	Fully biologically active when compared to standard. The specific activity determined by inducing differentiation of mouse M1 myeloid leukemic cells. The minmun detectable concentration of rHuLIF in this assay is 0.5 ng/ml.
Endotoxin Level	Less than 1EU/ug of rHuLIF as determined by LAL method.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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CS-CRL126C-datasheet.pdf

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Amount: 1 mg

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Delivery expected until 9/11/2025

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