Item no. |
CS-CRM101C |
Manufacturer |
Cell Sciences
|
Amount |
1.0 mg |
Category |
|
Type |
Proteins |
Specific against |
Human (Homo sapiens) |
Host |
E.coli |
Purity |
>97% by SDS-PAGE and HPLC analyses. |
Sequence |
GPYGANMEDS VCCRDYVRYR LPLRVVKHFY WTSDSCPRPG VVLLTFRDKE ICADPRVPWV KMILNKLSQ |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Similar products |
MDC, CC chemokine STCP-1, SCYA22, small inducible cytokine subfamily A (Cys-Cys), A-152E5.1, ABCD-1, DC/B-CK, MGC34554, STCP-1, macrophage-derived chemokine, small inducible cytokine A22, member 22, stimulated T cell chemotactic protein 1 |
Available |
|
Manufacturer - Category |
Biomolecules |
Storage Conditions |
Stable at 2-8C, but best kept desiccated -20C. Upon reconstitution, stable for up to 1 week at 2-8C. For longer term, store in working aliquots below -20C. Avoid repeated freeze/thaw cycles. |
Molecular Weight |
8.1 kDa |
Description |
Macrophage-Derived Chemokine/CCL22 (MDC) is a CC chemokine that is produced in B cells, macrophages, monocyte-derived dendritic cells, activated NK cells and CD4 T cells. It signals through the CCR4 receptor. MDC chemoattracts monocytes, dendritic cells and NK cells and exerts HIV suppressive activity. |
Formulation |
Lyophilized from a 0.2um filtered concentrated solution in 20 mM PB, pH7.4 + 500 mM NaCl. |
Reconstitution |
Centrifuge vial prior to opening. Add sterile distilled water or aqueous buffer to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in appropriate buffered solutions. |
Biological Activity |
Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human T-lymphocytes is less than 100 ng/ml |
Endotoxin Level |
Less than 1EU/ug of rHuMDC/CCL22 as determined by LAL method. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.