Comparison

Recombinant Human MSTN Propeptide

Item no. CS-CRM142B
Manufacturer Cell Sciences
Amount 25 ug
Category
Type Proteins
Specific against Human (Homo sapiens)
Host E.coli
Purity > 95.0% as determined by reducing and non-reducing SDS-PAGE and by UV spectroscopy at 280 nm.
Sequence MNENSEQKEN VEKEGLCNAC TWRQNTKSSR IEAIKIQILS KLRLETAPNI SKDVIRQLLP KAPPLRELID QYDVQRDDSS DGSLEDDDYH ATTETIITMP TESDFLMQVD GKPKCCFFKF SSKIQYNKVV KAQLWIYLRP VETPTTVFVQ ILRLIKPMKD GTRYTGIRSL KLDMNPGTGI WQSIDVKTVL QNWLKQPESN LGIEIKALDE NGHDLAVTFP GPGEDGLNPF LE
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Similar products GDF8, growth differentiation factor 8
Available
Manufacturer - Category
Biomolecules
Storage Conditions
Store lyophilized protein at -20C. Reconstituted material should be aliquoted and frozen at -20C. It is recommended that a carrier protein (0.1% HSA or BSA) is added for long term storage. Avoid repeated freeze-thaw cycles.
Molecular Weight
27.8 kDa
Description
Myostatin (GDF-8) is a member of the TGF-a superfamily and is a potent and specific negative regulator of skeletal muscle mass. The myostatin propeptide is known to bind and inhibit myostatin, in vitro . This interaction is relevant, in vivo , with a majority (>70%) of myostatin in serum bound to its propeptide acting as a negative regulator of myostatin. Recombinant Human Myostatin Propeptide is a non-glycosylated protein containing 244 amino acids.
Formulation
Sterile Filtered white lyophilized (freeze-dried) powder with no additives
Reconstitution
Centrifuge vial prior to opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile 20 mM HCl at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Biological Activity
The activity is determined by its ability to inhibit 50 ng/ml of Myostatin on MPC-11 cells and is typically 0.01-0.04 ug/ml.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25 ug
Available: In stock
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