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Recombinant Human Neuregulin-1-beta2 EGF-like Domain

Recombinant Human Neuregulin-1-beta2 EGF-like Domain

Item no.	CS-CRN005B
Manufacturer	Cell Sciences
Amount	100 ug
Category	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Signaling Neural Adhesion Molecules By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Adenocarcinoma By Organ Lung Cancer Bladder Cancer Colorectal Cancer Breast Cancer Neuronal Cell Markers
Type	Proteins
Specific against	Human (Homo sapiens)
Host	E.coli
Purity	>96.0% by HPLC and SDS-PAGE
Sequence	SHLVKCAEKE KTFCVNGGEC FMVKDLSNPS RYLCKCPNEF TGDRCQNYVM ASFYKAEELY Q
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	HRG, ARIA, GGF, GGF2, HGL, HRG1, HRGA, NDF, SMDF, glial growth factor, heregulin, alpha (45kD, ERBB2 p185-activator), neu differentiation factor, sensory and motor neuron derived factor, neuregulin 1 isoform HRG-gamma
Available
Manufacturer - Category	Biomolecules
Storage Conditions	Stable at 2-8C, but best kept desiccated -20C. Upon reconstitution, stable for up to 1 week at 2-8C. For longer term, store in working aliquots below -20C. Avoid repeated freeze/thaw cycles.
Molecular Weight	ca. 7.0 kDa
Description	Neuregulin is a signaling protein for ErbB2/ErbB4 receptor heterodimers on the cardiac muscle cells, playing an important role in heart structure and function through inducing ErbB2/ErbB4 receptor phosphorylation and cardiomyocyte differentiation. Research on molecular level discovered that recombinant neuregulin could make disturbed myocardial cell structure into order and strengthen the connection between myocardial cells by intercalated discs re-organization.
Formulation	Lyophilized from a 0.2 um filtered solution in 2 0 mM PB, pH 7.0, containing 0.5% HAS and 2% mannitol.
Reconstitution	Centrifuge vial prior to opening. Add sterile distilled water or aqueous buffer to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in appropriate buffered solutions.
Specificity	1.2 x 104 units/mg
Biological Activity	Fully biologically active when compared to standard. The ED50 determined by a cell proliferation assay using serum free human MCF-7 cells is less than 83 ng/ml.
Endotoxin Level	Less than 1EU/ug of rHuNRG-1/HRG1beta as determined by LAL method.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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CS-CRN005B-datasheet.pdf

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Amount: 100 ug

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Delivery expected until 8/7/2025

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