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Recombinant Human PKA c alpha GST Active

Recombinant Human PKA c alpha GST Active

Manufacturer	Cell Sciences
Category	Oncology By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins
Type	Proteins
Specific against	Human
Amount	10 ug
Host	Insect
Item no.	CS-CRP023B
Targets	PRKACA
Conjugate/Tag	GST
eClass 6.1	34160400
eClass 9.0	42020190
Available
Description	The catalytic subunit C-alpha of PKA (PKAca) is a member of the Ser/Thr protein kinase family and has been assigned to chromosome region 19p13.1. Null mutation in PKAca leads to early postnatal lethality in the majority of C-alpha knockout mice. Surprisingly, a small percentage of C-alpha knockout mice, although runted, survived to adulthood. In these animals, compensatory increases in C-beta levels occurred in brain whereas many tissues, including skeletal muscle, heart, and sperm, contained less than 10% of the normal PKA activity.
Formulation	Liquid in 50 mM Tris-HCl, pH 7.5 + 150 mM NaCl + 0.25 mM DTT + 0.1 mM EGTA + 0.1 mM EDTA + 0.1 mM PMSF + 25% glycerol
Molecular Weight	ca. 69 kDa
Storage and Stability	Store product at -80C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles .
Specificity	141 nmol/min/mg per activity assay protocol.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.