Recombinant Human PRKCG/PKC Gamma GST Active

Stable for 1 year in working aliquots at -80C. Avoid repeated freeze-thaw cycles.

Recombinant human full length PRKCG with N-terminal GST tag. PRKCG is a member of the protein kinase C (PKC) family of serine- and threonine-specific protein kinases that can phosphorylate a wide variety of protein targets known to be involved in diverse cellular signaling pathways. In the brain, PRKCG is translocated to cell membranes during ischemia and is rapidly removed or degraded during the second otherwise lethal ischemic insult in preconditioned brains. This suggest that ischemic preconditioning enhances downregulation of cell signaling mediated by PRKCG and may thereby provide neuroprotection.

512 nmol/min/mg