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Recombinant Human SERPINE1/PAI1 Active *di

Recombinant Human SERPINE1/PAI1 Active *di

Manufacturer	Cell Sciences
Category	Oncology Food Safety Proteins Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Senescence Cardiovascular Research Heart Failure Myocardial Infarction Hypertension By Organ Breast Cancer
Type	Proteins
Specific against	Human
Amount	0.5 mg
Host	E.coli
Item no.	CS-CRP173B
Targets	SERPINE1, AGT
eClass 6.1	34160400
eClass 9.0	42020190
Available
Biological Activity	>98% active as determined by titration with HMW tc-uPA and SDS-PAGE
Description	Plasminogen Activator Inhibitor 1 ((SERPINE1/PAI1) is the principal inhibitor of Tissue Plasminogen Activator (tPA) and Urokinase (uPA), the activators of Plasminogen and hence fibrinolysis. It is a serine protease inhibitor (serpin) protein (SERPINE1). PAI1 is mainly produced by the endothelium, but is also secreted by other tissue types, such as adipose tissue. Defects in the SERPINE1 gene are the cause of Plasminogen Activator Inhibitor 1 deficiency (PAI1 deficiency), and high concentrations of SERPINE1/PAI1 are associated with Thrombophilia.
Formulation	Frozen liquid in 0.05 M Sodium Phosphate + 0.1M NaCl + 1 mM EDTA, pH 6.6
Molecular Weight	43.0 kDa
Storage and Stability	Store in working aliquots at -80C. 3 years from delivery. Avoid repeated freeze-thaw cycles.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.