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Recombinant Human soluble RANK Ligand

Recombinant Human soluble RANK Ligand

Item no.	CS-CRR100B
Manufacturer	Cell Sciences
Amount	10 ug
Category	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Glucose Homeostasis Peptides & Proteins Recombinant Proteins Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis By Organ Lymphatic System Cancer
Type	Proteins
Specific against	Human (Homo sapiens)
Host	E.coli
Purity	98.0% as determined by Reducing and Non-reducing SDS-PAGE, UV spectroscopy at 280 nm
Sequence	MEKAMVDGSW LDLAKRSKLE AQPFAHLTIN ATDIPSGSHK VSLSSWYHDR GWAKISNMTF SNGKLIVNQD GFYYLYANIC FRHHETSGDL ATEYLQLMVY VTKTSIKIPS SHTLMKGGST KYWSGNSEFH FYSINVGGFF KLRSGEEISI EVSNPSLLDP DQDATYFGAF KVRDID
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	CD254, RANKL, ODF, OPGL, OPTB2, TRANCE, hRANKL2, sOdf, OTTHUMP00000178585, TNF-related activation-induced cytokine, osteoclast differentiation factor, osteoprotegerin ligand, receptor activator of nuclear factor kappa B ligand, RP11-86N24.2, tumor necrosis factor ligand superfamily member 11, receptor activator of nuclear factor kappa-B ligand
Available
Manufacturer - Category	Biomolecules
Storage Conditions	Lyophilized product is very stable at -20C. Reconstituted material should be aliquoted and frozen at -20C. It is recommended that a carrier protein (0.1% HSA or BSA) is added for long term storage. This depends upon the particular application employed. Avoid repeated freeze-thaw cycles.
Molecular Weight	20 kDa
Description	Receptor Activator of NF-kappaB Ligand (RANKL) is a cell-bound marker (CD254) related to the TNF family of proteins. RANKL plays a critical role in bone metabolism, particularly osteoclast differentiation. In addition, RANKL is expressed by some T cells is thought to promote dendritic cell maturation. Recombinant soluble human RANKL is a non-glycosylated protein, containing 176 amino acids.
Formulation	Recombinant soluble human RANKL is lyophilized from a concentrated (1mg/mL) solution containing 10 mM Na2PO4, pH 8.0.
Reconstitution	Centrifuge vial prior to opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Biological Activity	The activity is determined by a dose-dependent stimulation of IL-8 production in human PBMC and is typically less than 100 ng/mL.
Endotoxin Level	Measured by kinetic LAL analysis and is typically <=1 EU/ug protein.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 ug

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Delivery expected until 8/7/2025

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