Recombinant Human PON2 His

Store at 2-4C if entire vial will be used within 1-2 weeks. Store, frozen at -20C for longer periods of time. Avoid multiple freeze-thaw cycles.

Paraoxonase 2 (PON2) is a member of a multigene family whose genes share 65% identity at the amino acid level, and is expressed in a variety of tissues, including the pancreas. PON2 overexpression has been shown to lower the intracellular oxidative state and reduce the cells ability to oxidize LDL. PON2 is therefore implicated in the modulation of oxidative stress. Recombinant Human Paraoxonase-2 is expressed in, E. coli, , has a molecular weight of 43.5 kDa, and is fused to an N-terminal hexahistidine tag. It is purified by proprietary chromatographic techniques.