Comparison

Recombinant Human GTPase HRas G12V Mutant GST

Item no. CS-CSI11667
Manufacturer Cell Sciences
Amount 50 ug
Category
Type Proteins
Specific against Human (Homo sapiens)
Host E.coli
Conjugate/Tag GST
Purity >95% by SDS-PAGE.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Available
Manufacturer - Category
Biomolecules
Storage Conditions
Stable for 1 year at -80C. Avoid freeze / thaw cycles.
Description
Harvey rat sarcoma viral oncogene homolog, H-Ras (G12V)GST. Ras proteins are members of the superfamily of small GTP-binding proteins that function as molecular switches controlling a variety of signaling and transport pathways. H-Ras is one of the classic human Ras proteins (H-, N-, K-Ras4A, and K-Ras4B). The mutation G12V leads to elimination of the intrinsic GTPase activity. H-Ras (G12V) is effective in activation of PI3K and PKB, whereas N-Ras and K-Ras are more potent towards MAP kinase. The GST-Tag facilitates the protein’s application in typical GST pull-down assays.
Formulation
Liquid. Supplied as a 1 mg/ml solution in 25 mM Tris-HCl, pH 7.5, 150 mM NaCl, 5 mM MgCl2, and 5 mM a-mercaptoethanol.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
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