Native Human APOC1

Store at -20C. Avoid repeated freeze-thaw cycles.

Human Apolipoprotein CI (APOC1) is a lipoprotein with a length of 57 amino acids. Human APOC1 is one of the most positively charged proteins in the human body. The main function of APOC1 is inhibition of CETP, probably by altering the electric charge of HDL molecules. Recent studies have suggested that APOC1 in very low-density lipoprotein (VLDL) plays an important role in causing hypertriglyceridemia independent of APOC3, which is associated with coronary heart disease (CHD). APOC1 has been found to activate LCAT. The normal plasma concentration of APOC1 is 4-7 mg/dl.