Mouse Plasmin *di

Store at -70C.

Plasminogen (Plg) is a circulating zymogen that is converted to the active enzyme Plasmin by cleavage of the peptide bond between Arg-560 and Val-561, which is mediated by Urokinase (uPA/Plau) and Tissue Plasminogen Activator (tPA/Plat). The main function of Plasmin is to dissolve Fibrin blood clots. Plasmin, like Trypsin, belongs to the family of serine proteases Fibrin is a cofactor for Plasminogen activation by tPA. Urokinase Plasminogen Activator Receptor (uPAR) is a cofactor for Plasminogen activation by uPA. Plasmin is inactivated by Alpha-2-Antiplasmin, a serine protease inhibitor (serpin).

10.0 mg/mL