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Native Human Platelet Glycoprotein IIb/IIIa

Native Human Platelet Glycoprotein IIb/IIIa

Item no.	CS-CSI20171A
Manufacturer	Cell Sciences
Amount	1.0 mg
Category	Peptides & Proteins Native Proteins
Type	Proteins
Specific against	Human (Homo sapiens)
Host	Human
Purity	>95% by SDS-PAGE analysis
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Manufacturer - Category	Biomolecules
Storage Conditions	Store at -20C. Stable for 1 year from delivery. Avoid repeated freeze-thaw cycles.
Molecular Weight	Mixed
Description	Platelet membrane glycoproteins IIb and IIIa (GPIIb and GPIIIa) constitute the fibrinogen receptor and are required for platelet aggregation. Glycoprotein IIb consists of 2 disulfide-linked subunits GPIIb (MW = 125, 000) and GPII (MW= 23, 000) while GPIIIa has only one polypeptide chain (MW= 108, 000). GPIIbIIIa migrates on gels as follows: GPIIb 136, 000 non-reduced and 125, 000 reduced. GPIIIa is 97, 000 non-reduced and 108, 000 reduced. Protein concentration is determined via the Bradford method.
Formulation	Liquid in 0.02M Tris-HCl + 0.1M NaCl + 0.1% Triton X-100 + 0.001M CaCl2 + 0.05% NaN3 + 50% glycerol, pH 7.4. Sodium Azide used as a preservative.
Specificity	Positive by Heparin induced thrombocytopenia platelet activated assay (HIT Test)
Concentration	2.0 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1.0 mg

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Delivery expected until 8/21/2025

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